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 Entacapone Chemical-data

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HOME >> API >> API List1 >> Entacapone >> Dosage

Molecular Formula C14H15N3O5

DOSAGE
Entacapone CAS Number 130929-57-6

This medicine is taken by mouth, with or without food Entacapone generally is taken at the same time as your levodopa/carbidopa medicine, or as directed. Follow all instructions carefully; you may need to decrease the dosage of your levodopa/carbidopa, depending on the amount of levodopa you currently take. Your levodopa/carbidopa dosing schedule may change as well. Do not suddenly stop using this drug: the dosage should be reduced gradually to minimize possible side effects. Consult your doctor or pharmacist for more information. The manufacturer advises a maximum of 8 doses per day.

Entacapone is always used in combination with carbidopa and levodopa; it has no activity against Parkinson's disease when used alone. The drug works by increasing blood levels of levodopa and helping levodopa to last longer in the body. Entacapone works by inhibiting an enzyme known as catechol-O-methyltransferase (COMT) that breaks down levodopa before it has a chance to reach the brain.

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