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HOME >> API >> API List 3 >> Repaglinide >> Interaction

INTERACTION
Repaglinide CAS number 135062-02-1

Repaglinide should not be used with the following medication because very serious effects (very low blood sugar) may occur: gemfibrozil. If you are currently using this medication, tell your doctor or pharmacist before starting repaglinide. Fenofibrate may be an alternative medication for the gemfibrozil. Also, itraconazole should not be used in combination with repaglinide and gemfibrozil because extremely low blood sugar could occur. Tell your doctor of all nonprescription and prescription medication you may use, especially: beta-blocker type drugs (e.g., propranolol, metoprolol), NSAIDs (e.g., aspirin, ibuprofen), sulfa drugs (e.g., sulfamethoxazole), chloramphenicol, "blood thinners" (e.g., warfarin), probenecid, MAO Inhibitors (e.g., phenelzine, tranylcypromine, selegiline, furazolidone), "water pills" (e.g., thiazides, furosemide), corticosteroids, phenothiazines (e.g., chlorpromazine), thyroid drugs, estrogens and birth control pills, niacin, "adrenaline-like" drugs (e.g., pseudoephedrine), "calcium blockers" (e.g., verapamil), isoniazid (INH), drugs which affect certain liver enzymes (CYP 3A4 inhibitors and inducers such as azole antifungals- e.g., ketoconazole, macrolide antibiotics- e.g., clarithromycin, cimetidine, rifamycins- e.g., rifampin, St John's wort, certain anti-seizure medications- e.g., phenytoin). Check all medicine labels (including nonprescription drugs) since many products contain "adrenaline-like" drugs. Consult your pharmacist. Do not start or stop any medicine without doctor or pharmacist approval.

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