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Phenobarbital Sodium
>> Interaction
INTERACTION
Phenobarbital sodium
CAS Registry Number 57-30-7
This drug should not be used with the following medications because very
serious interactions may occur: etravirine, sodium oxybate, delavirdine,
darunavir, voriconazole.
Some other drowsiness-causing medications may cause serious (possibly fatal)
slowed breathing when taken with higher doses of phenobarbital. Tell your
doctor or pharmacist if you also take other drugs that cause drowsiness such
as: medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem),
muscle relaxants (e.g., methocarbamol), narcotic pain relievers (e.g.,
codeine), psychiatric medicines (e.g., chlorpromazine, risperidone,
amitriptyline, trazodone).
If you are currently using any of these medications listed above, tell your
doctor or pharmacist before starting phenobarbital.
Before using this medication, tell your doctor or pharmacist of all
prescription and nonprescription/herbal products you may use, especially of:
warfarin, estrogens (e.g., some birth control pills/hormone replacement
treatments), corticosteroids (e.g., prednisone, dexamethasone), quinidine,
felodipine, certain beta blockers (acebutolol, betaxolol, carteolol,
metoprolol, propranolol), metronidazole, doxycycline, certain antifungal
medications (griseofulvin, posaconazole), phenytoin, valproic acid,
cyclosporine, sunitinib, dasatinib, erlotinib, irinotecan, telithromycin,
theophylline, MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid,
moclobemide, phenelzine, procarbazine, rasagiline, selegiline,
tranylcypromine).
This medication can speed up the removal of many other drugs from your body
by affecting certain liver enzymes. This can affect how well these other
drugs work. Tell your doctor or pharmacist of all other drugs you take.
Before using this medication, tell your doctor or pharmacist if you use any
other prescription and nonprescription products that cause drowsiness such
as certain antihistamines (e.g., diphenhydramine) and anti-seizure drugs
(e.g., carbamazepine).
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