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morphine and codeine

HOME >> API >> API List 4 >> Thebaine >> Drug Description

DRUG DESCRIPTION
Thebaine CAS number 115-37-7

Thebaine is an opiate alkaloid. A minor constituent of opium, thebaine is chemically similar to both morphine and codeinebut has stimulatory rather than depressant effects, causing strychnine-like convulsions at higher doses.[3] Thebaine is not used therapeutically, but can be converted industrially into a variety of compounds including oxycodone, oxymorphone, nalbuphine, naloxone, naltrexone, buprenorphine and etorphine.

Thebaine, a minor constituent of opium, is controlled in Schedule II of the CSA as well as under international law. Although chemically similar to both morphine and codeine, thebaine produces stimulatory rather than depressant effects. Thebaine is not used therapeutically, but is converted into a variety of substances including oxycodone, oxymorphone, nalbuphine, naloxone, naltrexone, and buprenorphine

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