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DRUG DESCRIPTION
Codeine base
CAS number 76-57-3
Codeineis an opiate used for its analgesic, antitussive and antidiarrheal
properties. It is by far the most widely used opiate in the world and
probably the most commonly used drug overall according to numerous reports
over the years by organizations such as the World Health Organization and
its League of Nations predecessor agency and others. It is one of the most
effective orally-administered analgesics and has a wide safety margin.
It is from 8 to 12 percent of the strength of morphine in most people;
differences in metabolism can change this figure as can other medications.
Codeine is in a group of drugs called narcotic pain medicines.
Codeine is used to treat mild to moderate pain.
Codeine may be habit-forming and should be used only by the person it was
prescribed for. Codeine should never be given to another person, especially
someone who has a history of drug abuse or addiction. Keep the medication in
a secure place where others cannot get to it. Do not drink alcohol while you
are taking codeine. Dangerous side effects or death can occur when alcohol
is combined with a narcotic pain medicine. Check your food and medicine
labels to be sure these products do not contain alcohol. Never take more
than your prescribed dose of codeine. Tell your doctor if the medicine seems
to stop working as well in relieving your pain. Codeine can cause side
effects that may impair your thinking or reactions. Be careful if you drive
or do anything that requires you to be awake and alert. Do not stop using
codeine suddenly, or you could have unpleasant withdrawal symptoms. Talk to
your doctor about how to avoid withdrawal symptoms when stopping the
medication.
Codeine is a member of the drug class opiates. Opiates include all naturally
occurring drugs with morphine-like effects such as codeine and all semi and
fully synthetic drugs with morphine-like effects such as heroin and
meperidine . Codeine was first discovered as a natural constituent of opium
in very small concentrations, in the range of 0.7% - 2.5% by weight. Most
codeine found in pharmaceutical products today is synthetically produced via
the methylation of morphine.
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