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Gabapentin

HOME >> API >> API List 2 >> Gabapentin >> Dosage

DOSAGE
Gabapentin CAS number 60142-96-3

Gabapentin may be taken with or without food. The recommended dose for postherpetic neuralgia is 1800 mg daily in 3 divided doses. The initial dose of 300 mg daily is increased over several days to the recommended daily dose. Seizures are treated with 900-1800 mg/daily in 3 divided doses. Withdrawal of treatment should occur slowly over a week.

Take this medication by mouth, with or without food, as directed by your doctor. The dosage is based on your medical condition and response to therapy. During the first few days, your doctor may gradually increase your dose so your body can adjust to the medication. To minimize side effects, take the very first dose at bedtime. Use this medication regularly in order to get the most benefit from it. This drug works best when the amount of medicine in your body is kept at a constant level. Therefore it is best to take gabapentin at evenly spaced intervals throughout the day and night. Do not take this medication more often or increase your dose without consulting your doctor. Your condition will not improve any faster and the risk of serious side effects may be increased. Do not stop taking this medication without consulting your doctor. Some conditions such as seizures may become worse when the drug is abruptly stopped. Your dose may need to be gradually decreased. Antacids containing aluminum or magnesium may interfere with the absorption of this medication. Therefore it is best to take gabapentin at least 2 hours after taking an antacid.

For adults, the initial dose of gabapentin is 300 mg taken by mouth three times each day. The dosage may be increased if necessary. Dosages as high as 800–1,200 mg three times daily have been well tolerated.

In children three to 12 years of age, the starting dose should be 10–15 mg/2.2 lb (1 kg)/day given in three equal doses. This dose can be increased until an effective dosage is reached, typically 25–40 mg/2.2 lb (1 kg)/day. Lower dosages are required for patients that have kidney disease.

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