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HOME >> API >> API List 2 >> Ibandronate Sodium >> Precautions

PRECAUTIONS
Ibandronate Sodium CAS Number 138926-19-9

* Ibandronate, like all bisphosphonate medications, can irritate or damage the esophagus and stomach. This can lead to indigestion, heartburn, or even ulcers. Let your healthcare provider know if you notice any of these problems while taking the drug.

* It is important to get enough calcium and vitamin D (either through your diet or by supplementation). Calcium and vitamin D are necessary for rebuilding bone and preventing further bone loss.

* Ibandronate may not be recommended for people with severe kidney disease.

* In rare cases, bisphosphonates (including ibandronate) have caused a condition called osteonecrosis of the jaw. This is a serious, possibly disfiguring, problem in which the bone of the jaw dies. Often, there are symptoms (such as pain, infection, or loosening of the teeth), but sometimes there are no symptoms until a person notices exposed bone.

This problem is most common when bisphosphonates are given by IV (but is still possible when these medications are taken orally). It seems that people who have dental procedures (such as a tooth extraction) are also at higher risk. Be sure to take good care of your mouth and teeth by seeing your dentist frequently. Let your healthcare provider know right away if you think you may have osteonecrosis of the jaw.

* In rare cases, bisphosphonates (including ibandronate) can cause extreme muscle or bone pain. This usually goes away once the medication is stopped.

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