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HOME >> API >> API List 2 >> Irinotecan Hcl >> Dosage

DOSAGE
Irinotecan Hcl CAS Registry Number 100286-90-6

Irinotecan may be given:

* as a drip (infusion) through a fine tube (cannula) inserted into a vein
* through a central line, which is inserted under the skin into a vein near the collarbone, or into a PICC line, which is inserted into a vein in the crook of your arm.

Chemotherapy is usually given as a course of several sessions (or cycles) of treatment over a few months. The length of your treatment and the number of cycles you have will depend on the type of cancer for which you are being treated. Irinotecan is commonly given alongside other chemotherapy drugs as part of a combination regimen. Your nurse or doctor will discuss your treatment plan with you.
Irinotecan is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting. The medicine must be given slowly through an IV infusion, and can take up to 90 minutes to complete. The irinotecan injection is usually followed by infusions with other cancer medications. These combination chemotherapy treatments are usually given at weekly intervals for several weeks.

Before starting your irinotecan injection, you may be given medications to help prevent nausea, vomiting, diarrhea, and other side effects. You may also need to use some of these medications for at least a day after your irinotecan injection.
Irinotecan can cause severe diarrhea, which can be life-threatening if it leads to dehydration. Diarrhea can occur soon after your injection or more than 24 hours later.

Your doctor may recommend you have an anti-diarrhea medicine such as loperamide (Imodium) available at all times while you are receiving irinotecan. The anti-diarrhea medication is usually taken at the first sign of loose or frequent bowel movements.

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