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HOME >> API >> API List 2 >> Letrozole >> Side Effects

Letrozole Molecular Formula C17H11N5

Letrozole CAS Registry Number 112809-51-5

Each person's reaction to any medication is different. Most people have very few side effects with Femara, while others may experience more. The side effects described in this information will not affect everyone and may be different if you are having more than one drug.

We have outlined the most common side effects. However, we have not included those which are very rare and extremely unlikely to affect you.

If you notice any effects that you think may be due to the drug, but which are not listed in this information, please discuss them with your doctor or nurse.

You will see your doctor regularly while you have this treatment so that they can monitor you.

Some people may have the following side effects to varying degrees:

Feeling sick (nausea), and being sick (vomiting) These effects are rare and usually mild. Feelings of sickness can often be relieved by taking your tablet with food or milk, or at night. Let your doctor know if any of these effects are troublesome, as medicines can usually be prescribed to control them.

Tiredness and headaches These are not common. It is important to get enough rest. Let your doctor know if you are getting headaches, as medicines can be prescribed to help.

Muscular aches and joint pain These are rare, but if they occur let your doctor know, as medication may be prescribed.

Hot flushes These are usually mild and may wear off after a period of time. Some people find that it is helpful to cut down on tea, coffee, nicotine and alcohol. Recent research suggests that progestogen or some types of antidepressants may be helpful in controlling this side effect. Your nurse or doctor can discuss this with you.

Some women have found complementary therapies helpful. Your GP may be able to give you details about obtaining these on the NHS.

Hair thinning Some women notice that their hair thins while taking Femara, although this is usually mild.

Vaginal dryness This may occur while using Femara. Gels that can help to overcome the dryness are available. The gels can be bought from any chemist or can be prescribed by your doctor.

Risk of osteoporosis Women who have osteoporosis (weakened bones) or are at risk of it, should have their bones assessed before and during treatment with Femara. In some situations it may be necessary to start treatment to help prevent osteoporosis.


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