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Noscapine HCl
M.Wt: 449.88
Formula: C22H23NO7.HCl
Solubility: Soluble to 50 mM in 1eq. HCl
Purity: >99 %
Storage: Desiccate at RT
CAS No: [912-60-7]
Chemical Name: (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy
-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-iso benzofuranone
hydrochloride
Biological Activity:
Opioid alkaloid with several actions. Binds to tubulin, arresting cells in
mitosis and inducing apoptosis. Also is an antagonist at bradykinin
receptors (pA2 = 6.68), inhibits carbachol-stimulated phosphoinositol
turnover and enhances forskolin-stimulated increases in cAMP levels in CNS
tissues. Clinically used antitussive agent.
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