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Noscapine base tablets

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HOME >> API >> API List 4 >> Noscapine Base >> Other Information

OTHER INFORMATION
Noscapine base CAS Number 128-62-1

Possible side-effects

* Loss of coordination
* Hallucinations (auditory and visual)
* Loss of sexual drive
* Swelling of prostate
* Loss of appetite
* Dilated pupils
* Increased heart rate
* Shaking and muscle spasms
* Chest pains
* Increased alertness
* Loss of any sleepiness
* Loss of stereoscopic vision

Noscapine in Heroin

Noscapine can survive the manufacturing processes of heroin and can be found in street heroin. This is useful for law enforcement agencies, as the amounts of contaminants can identify the source of seized drugs. In 2005 in Liège, Belgium, the average noscapine concentration was around 8%.[7]

Noscapine has also been used to identify drug users who are taking street heroin at the same time as prescribed diamorphine.[8] Since the diamorphine in street heroin is the same as the pharmaceutical diamorphine, examination of the contaminants is the only way to test whether street heroin has been used. Other contaminants used in urine samples alongside noscapine include papaverine and acetylcodeine. Noscapine is metabolised by the body, and is itself rarely found in urine, instead being present as the primary metabolites, cotarnine and meconine. Detection is performed by gas chromatography-mass spectrometry or Liquid Chromatography-Mass Spectrometry (LCMS) but can also use a variety of other analytical techniques.

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