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HOME >> API >> API List 3 >> Pamidronate Disodium >> Consumer Information

Disodium pamidronate CAS Number 109552-15-0


Pamidronate Disodium  CAS Number 109552-15-0

: This medication is used to treat high blood calcium levels (hypercalcemia) that may occur with cancer. Pamidronate is also used to treat a certain type of bone disease (Paget's disease) and bone problems that may occur with certain cancers (breast cancer, multiple myeloma). Pamidronate belongs to a class of drugs known as bisphosphonates. It works by reducing the amount of calcium released from your bones into your blood.

HOW TO USE: Follow all instructions for proper mixing and dilution with the correct IV fluids. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Do not mix this drug with solutions that contain calcium (e.g., lactated Ringer's solution). If you have questions regarding the use of this medication, consult your pharmacist. The dosage is based on your medical condition and response to therapy. The dose should not be greater than 90 milligrams or be given over less than 2 hours. Doses that are higher than 90 milligrams, doses given too quickly, or previous use of this medication increase the risk for kidney problems. For high calcium levels, one dose is usually given. If needed, a repeat dose may be given after 7 days.For Paget's disease, this drug is usually given once a day for 3 days or as directed by your doctor. For bone problems, use as directed by your doctor.

SIDE EFFECTS: Mild fever, redness/swelling/pain at the injection site, stomach pain, loss of appetite, dizziness, headache, nausea, vomiting, or constipation may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.

PRECAUTIONS: Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, asthma, severe loss of body water (dehydration), thyroid surgery. This drug may make you dizzy or lightheaded. Use caution while driving, using machinery, or doing any other activity that requires alertness. Limit alcoholic beverages.

MISSED DOSE: It is important to receive each dose as scheduled. If you miss a dose, contact your doctor for a new schedule.

STORAGE: Store the unmixed vials at room temperature between 56-86 degrees F (13-30 degrees C) away from light and moisture. This medication must be diluted with IV fluids just before use. However, the mixed vial can be refrigerated at 36-46 degrees F (2-8 degrees C) for 24 hours. Discard the mixed vial after 24 hours. Discard any unused portion of the vial. Keep all medicines away from children
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed.

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