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HOME >> API >> API List 3 >> Venlafaxine Hcl >> Drug Description

Venlafaxine Hcl  CAS Registry Number 99300-78-4

DRUG DESCRIPTION

Venlafaxine Hcl CAS Registry Number 99300-78-4


Venlafaxine hydrochloride is a white to off-white crystalline solid with a solubility of 572 mg/mL in water (adjusted to ionic strength of 0.2 M with sodium chloride). It s octanol: water (0.2 M sodium chloride) partition coefficient is 0.43.

Venlafaxine hydrochloride  is formulated as an extended-release capsule for once-a-day oral administration. Drug release is controlled by diffusion through the coating membrane on the spheroids and is not pH dependent. Capsules contain venlafaxine hydrochloride equivalent to 37.5 mg, 75 mg , or 150 mg venlafaxine. Inactive ingredients consist of cellulose, ethylcellulose, gelatin, hypromellose, iron oxide, and titanium dioxide.

 (Venlafaxine) is an antidepressant medication. It affects chemicals in your brain that may become unbalanced and cause depression. Venlafaxine is used to relieve symptoms of depression such as feelings of sadness, worthlessness, or guilt; loss of interest in daily activities; changes in appetite; tiredness; sleeping too much; insomnia; and thoughts of death or suicide. Venlafaxine is also used to relieve symptoms of generalized anxiety disorder. It is also being prescribed by some doctors as Migraine preventive.

Venlafaxine is used to treat depression. Venlafaxine extended-release (long-acting) capsules are also used to treat generalized anxiety disorder (excessive worrying that is difficult to control), social anxiety disorder (extreme fear of interacting with others or performing in front of others that interferes with normal life), and panic disorder (sudden, unexpected attacks of extreme fear and worry about these attacks). Venlafaxine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SNRIs). It works by increasing the amounts of serotonin and norepinephrine, natural substances in the brain that help maintain mental balance.

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