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CONSUMER INFORMATION
Ziprasidone Hcl
CAS Registry Number 138982-67-9
Warnings
There may be a slightly increased risk of serious, possibly fatal side
effects (e.g., stroke, heart failure) when this medication is used in
elderly patients with dementia. Discuss the risks and benefits of this
medication, as well as other effective and possibly safer treatments for
dementia-related behavior problems, with your doctor.
Uses
This medication is used to treat certain mental/mood disorders
(schizophrenia or manic/mixed episodes associated with bipolar disorder). It
may be used after other medications have not been effective. Ziprasidone is
a psychiatric medication (anti-psychotic type) that works by helping to
restore the balance of certain natural substances (neurotransmitters) in the
brain.
Side Effects
Dizziness, drowsiness, weakness, nausea, vomiting, runny nose, and cough may
occur. If any of these effects persist or worsen, notify your doctor or
pharmacist promptly.
This medication may rarely cause a very serious condition called serotonin
syndrome. The risk may increase when this medication is used with certain
other drugs such as "triptans" used to treat migraine headaches (e.g.,
sumatriptan, eletriptan), certain antidepressants including SSRIs (e.g.,
citalopram, paroxetine) and SNRIs (e.g., duloxetine, venlafaxine), lithium,
tramadol, tryptophan, or a certain drug to treat obesity (sibutramine).
Before taking this drug, tell your doctor if you take any of these
medications. Seek immediate medical attention if you develop some of the
following symptoms: hallucinations, unusual restlessness, loss of
coordination, fast heartbeat, severe dizziness, unexplained fever, severe
nausea/vomiting/diarrhea, twitchy muscles.
Precautions
This medication should not be used if you have certain medical conditions.
Before using this medicine, consult your doctor or pharmacist if you have:
certain heart problems (e.g., heart rhythm problems such as QTc
prolongation, recent heart attack, untreated heart failure).
Before using this medication, tell your doctor or pharmacist your medical
history, especially of: Alzheimer's disease, heart problems (e.g., coronary
artery disease, heart failure, irregular heartbeat, low blood pressure),
severe dizziness/fainting, diabetes (including family history), liver
disease, nervous system problems (e.g., stroke, seizures, NMS), obesity,
swallowing problems, aspiration pneumonia.
MISSED DOSE
If you miss a dose, take it as soon as you remember. If it is near the time
of the next dose, skip the missed dose and resume your usual dosing
schedule. Do not double the dose to catch up.
STORAGE
Store at room temperature between 59-86 degrees F (15-30 degrees C) away
from light and moisture. Do not store in the bathroom. Keep all medicines
away from children and pets.
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