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Alfuzosin
CAS number 81403-80-7


Identifiers

ATC code G04CA01
PubChem 2092
DrugBank APRD00490
ChemSpider 2008

Chemical data

Formula C19H27N5O4
Molecular Weight: 425.91

Pharmacokinetic data

Bioavailability 49%
Protein binding 82%-90%
Metabolism Hepatic (CYP3A4-mediated)
Half life 10 hours
Excretion Fecal (69%) and renal (24%)
 
What is alfuzosin?

Alfuzosin is in a group of drugs called alpha-adrenergic blockers. Alfuzosin helps relax the muscles in the prostate and bladder neck, making it easier to urinate.Alfuzosin is used to treat benign prostatic hyperplasia (enlarged prostate).Alfuzosin may also be used for other purposes not listed in this medication guide.

Alfuzosin Dosing Information

Usual Adult Dose for Benign Prostatic Hyperplasia:

10 mg orally once a day immediately after the same meal each day.

DRUG DESCRIPTION

Alfuzosin hydrochloride is a white to off-white crystalline powder that melts at approximately 240°C. It is freely soluble in water, sparingly soluble in alcohol, and practically insoluble in dichloromethane. Alfuzosin hydrochloride is (R,S)-N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl) methylamino] propyl] tetrahydro-2-furancarboxamide hydrochloride. The empirical formula of alfuzosin hydrochloride is C19H27N5O4•HCl.

DIN (Drug Identification Number)

02315866 APO-ALFUZOSIN 10MG TABLET

Chemical Data

Alfuzosin Systematic (IUPAC) name N-[3-[(4-amino-6,7-dimethoxy-quinazolin-2-yl)- methyl-amino]propyl] tetrahydrofuran- 2-carboxamide Identifiers CAS number 81403-80-7 ATC code G04CA01 PubChem 2092 DrugBank APRD00490 Chemical data Formula C19H27N5O4  Mol. weight 389.449 g/mol Pharmacokinetic data Bioavailability 49% Protein binding 82%-90% Metabolism Hepatic (CYP3A4-mediated) Half life 10 hours Excretion Fecal (69%) and renal (24%) Therapeutic con....

Storage

Store Uroxatral at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Uroxatral out of the reach of children and away from pets.

Chemical formulas

C₁₉H₃₀N₃O₄ · HCl 2H₂O,   Alfuzosin hydrochloride is C19H27N5O4•HCl, Molecular Formula: C6H10ClNO4,
 

Information Associated with Product :

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