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Atorvastatin Calcium
Cas No 134523-03-8

Chemical Formulas
 


Systematic (IUPAC) name
(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid

Identifiers

CAS number 134523-00-5
ATC code C10AA05
PubChem 60823
DrugBank APRD00055
ChemSpider 54809

Chemical data

Formula C33H35FN2O5
Mol. mass 558.64
SMILES eMolecules & PubChem

Pharmacokinetic data

Bioavailability 12%
Metabolism Hepatic - CYP3A4
Half life 14 hours
Excretion Bile
Therapeutic considerations
Pregnancy cat.
Routes oral

Atorvastatinis a member of the drug class known as statins, used for lowering blood cholesterol.

It also stabilizes plaque and prevents strokes through anti-inflammatory and other mechanisms.Atorvastatin inhibits HMG-CoA reductase, the rate-determining enzyme located in hepatic tissue that produces mevalonate, a small molecule used in the synthesis of cholesterol and other mevalonate derivatives.

This lowers the amount of cholesterol produced which in turn lowers the total amount of LDL cholesterol.


Information Associated with Product :  

Dosage
Uses
Side Effects

                               
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