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HOME >> Pharmaceuticals API List 1 >> Enalapril Maleate >> Drug Description

DRUG DESCRIPTION
Enalapril Maleate CAS number CAS 76095-16-4

Enalapril maleate is a high blood pressure medication known as an ACE inhibitor. It works by preventing a chemical in your blood called angiotensin I from converting into a more potent form that increases salt and water retention in your body. It is effective when used alone or in combination with other medications, especially thiazide-type diuretics. It is also used in the treatment of congestive heart failure, usually in combination with diuretics and digitalis, and is prescribed as a preventive measure in certain conditions that could lead to heart failure.

If you have high blood pressure, you must take Enalapril maleate regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Enalapril maleate ; and you must continue taking it even if you are feeling well. Enalapril maleate does not cure high blood pressure; it merely keeps it under control.

Enalapril maleate is a white to off-white, crystalline powder with a molecular weight of 492.53. It is sparingly soluble in water, soluble in ethanol, and freely soluble in methanol.

Enalapril is a pro-drug; following oral administration, it is bioactivated by hydrolysis of the ethyl ester to enalaprilat, which is the active angiotensin converting enzyme inhibitor.

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