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Fluoxetine capsulesand fluoxetine oral solutionis a selective serotonin reuptake inhibitor for oral administration.

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HOME >> Pharmaceuticals API List 1 >> Fluoxetine HCl >> Precautions

PRECAUTIONS
Fluoxetine HCl CAS number 54910-89-3

Do not use fluoxetine if you are using any of the following drugs:

*pimozide
*thioridazine or
oran MAO inhibitor such as isocarboxazid tranylcypromine phenelzinerasagilineor selegiline.

Serious and sometimes fatal reactions can occur when these medicines are taken with fluoxetine. You must wait at least 14 days after stopping an MAO inhibitor before you can take fluoxetine. You must wait 5 weeks after stopping fluoxetine before you can take thioridazineor an MAOI.

Before taking fluoxetine, tell your doctor if you are allergic to any drugs, or if you have:

*cirrhosis of the liver;
*kidney disease;
*diabetes;
*seizures or epilepsy;
*bipolar disorder (manic depression); or
*a history of drug abuse or suicidal thoughts.

If you have any of these conditions, you may not be able to use fluoxetine, or you may need a dosage adjustment or special tests.

You may have thoughts about suicide while taking an antidepressant, such as fluoxetine, especially if you are younger than 24 years old. Tell your doctor if you have worsening depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

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