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DOSAGE
Pantoprazole CAS number 102625-70-7
Pantoprazole comes as a delayed-release (long-acting) tablet to take by
mouth. It is usually taken once or twice a day with or without food. To help
you remember to take pantoprazole, take it around the same time every day.
Follow the directions on your prescription label carefully, and ask your
doctor or pharmacist to explain any part you do not understand. Take
pantoprazole exactly as directed. Do not take more or less of it or take it
more often than prescribed by your doctor.
Swallow the tablets whole; do not split, chew, or crush them.
Continue to take pantoprazole even if you feel well. Do not stop taking
pantoprazole without talking to your doctor.
Treatment of Erosive Esophagitis
The recommended adult oral dose is 40 mg given once daily for up to 8 weeks.
For those patients who have not healed after 8 weeks of treatment, an
additional 8-week course of Pantoprazole may be considered
Maintenance of Healing of Erosive Esophagitis
The recommended adult oral dose is Pantoprazole 40 mg, taken daily
Pathological Hypersecretory Conditions Including Zollinger-Ellison Syndrome
The dosage of Pantoprazole in patients with pathological
hypersecretory conditions varies with the individual patient. The
recommended adult starting dose is 40 mg twice daily. Dosage regimens should
be adjusted to individual patient needs and should continue for as long as
clinically indicated. Doses up to 240 mg daily have been administered. Some
patients have been treated continuously with Pantoprazole for more
than 2 years.
No dosage adjustment is necessary in patients with renal impairment, hepatic
impairment, or for elderly patients. Doses higher than 40 mg/day have not
been studied in hepatically-impaired patients. No dosage adjustment is
necessary in patients undergoing hemodialysis.
Pantoprazole Delayed-Release Tablets should be swallowed whole, with
or without food in the stomach. If patients are unable to swallow a 40 mg
tablet, two 20 mg tablets may be taken. Concomitant administration of
antacids does not affect the absorption of Pantoprazole
Delayed-Release Tablets.
Pantoprazole For Delayed-Release Oral Suspension should be
administered in applesauce or apple juice approximately 30 minutes prior to
a meal. See Administration Options subsection below. Patients should be
cautioned that Pantoprazole Delayed-Release Tablets and Pantoprazole
For Delayed-Release Oral Suspension should not be split, chewed or crushed.
Pantoprazole For Delayed-Release Oral Suspension should only be
administered in apple juice or applesauce, not in water or other liquids, or
foods.
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