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Side Effects
SIDE EFFECTS
Testosterone CAS number 58-22-0
less common adverse reactions, reported in fewer than 1% of patients
included: amnesia, anxiety, discolored hair, dizziness, dry skin, hirsutism,
hostility, impaired urination, paresthesia, penis disorder, peripheral
edema, sweating, and vasodilation.
Hypogonadal Men
Blood and the lymphatic system disorders: Elevated Hgb, Hct (polycythemia)
Endocrine disorders: Hirsutism
Gastrointestinal disorders: Nausea
General disorders and administration site reactions: Asthenia, edema,
malaise
Genitourinary disorders: Impaired urination
Hepatobiliary disorders: Abnormal liver function tests (e.g. transaminases,
elevated GCTP, bilirubin)
Investigations: Elevated PSA, electrolyte changes (nitrogen, calcium,
potassium, phosphorus, sodium), changes in serum lipids (hyperlipidemia,
elevated triglycerides, decreased HDL), impaired glucose tolerance,
fluctuating testosterone levels, weight increase
Neoplasms benign, malignant and unspecified (cysts and polyps): Prostate
cancer
Nervous system: Headache, dizziness, sleep apnea, insomnia
Psychiatric disorders: Depression, emotional lability, decreased libido,
nervousness, hostility, amnesia, anxiety
Reproductive system and breast disorders: Gynecomastia, mastodynia,
prostatic enlargement, testicular atrophy, oligospermia, priapism (frequent
or prolonged erections)
Respiratory disorders: Dyspnea
Skin and subcutaneous tissue disorders: Acne, alopecia, application site
reaction (pruritus, dry skin, erythema, rash, discolored hair, paresthesia),
sweating
Vascular disorders: Hypertension, vasodilation (hot flushes)
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