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HOME >> API >> API List 3 >> Zoledronic Acid >> Consumer Information

CONSUMER INFORMATION
Zoledronic Acid CAS Registry Number 165800-06-6

Uses

This medication is used to treat high blood calcium levels (hypercalcemia) that may occur with cancer. Zoledronic acid is also used to treat bone problems that may occur with a certain type of cancer (multiple myeloma) and other types of cancer. Zoledronic acid belongs to a class of drugs known as bisphosphonates. It works by reducing the amount of calcium released from your bones into your blood.

Side Effects

Nausea, stomach pain, vomiting, dizziness, diarrhea, flu-like symptoms (e.g., fever, chills, muscle/joint aches), or pain/redness/swelling at the injection site may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Tell your doctor immediately if any of these unlikely but serious side effects occur: increased or severe bone/joint/muscle pain, jaw pain, unusual weakness, unusual tiredness, trouble sleeping, trouble swallowing, eye problems (e.g., "pinkeye"/conjunctivitis), vision problems (e.g., trouble seeing), swelling legs, numb/tingling skin, fast/pounding/irregular heartbeat, persistent sore throat with fever, unusual bruising/bleeding, change in the amount of urine, burning/painful urination, mental/mood changes (e.g., agitation, anxiety, confusion).

Precautions

Before using zoledronic acid, tell your doctor or pharmacist if you are allergic to it; or to other bisphosphonates such as alendronate, risedronate; or if you have any other allergies.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, asthma, severe loss of body water (dehydration).

Infrequently, serious jawbone problems (osteonecrosis) have occurred in people using this medication. Most people were also using other medications or had conditions that might have caused the jawbone problem. If you have cancer, anemia, blood clotting disorders, infections/other diseases of the mouth, or poor dental hygiene, see your dentist for a full examination/treatment before you start zoledronic acid. Tell your dentist that you will be using zoledronic acid, and make sure he or she knows of all your medications, especially corticosteroids (e.g., prednisone) and cancer chemotherapy. Also tell him or her of your entire medical history, especially of any cancer radiation treatments.

MISSED DOSE

It is important to receive each dose as scheduled. If you miss a dose, contact your doctor for a new schedule.

STORAGE

Store the unmixed vials at room temperature between 56-86 degrees F (13-30 degrees C) away from light and moisture. After mixing with IV fluids, this product should be refrigerated between 36-46 degrees F (2-8 degrees C) and used within 24 hours. Discard the mixed drug after 24 hours. Discard any unused portion of the vial. Keep all medicines away from children and pets.

Information Associated with Product:
DRUG DESCRIPTION DOSAGE SIDE EFFECTS PRECAUTIONS INTERACTION CONSUMER INFORMATION >>
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