>> Benzyl methyl ketone
Phenylacetone, Benzyl methyl ketone, Phenyl-2-propanone,
1-Phenylacetone, Methyl benzyl ketone, 1-Phenyl-2-propanone,
phenyl acetone, 2-Propanone, 1-phenyl-, 3-Phenyl-2-propanone,
Phenylmethyl methyl ketone, 1-phenylpropan-2-one, BENZYLMETHYL
KETONE, DEA No. 8501, ghl.PD_Mitscher_leg0.660, NSC 9827,
CHEBI:52052, EINECS 203-144-4, NSC9827, CPD-7233, ZINC01700205
CAS Registry Number: 103-79-7
Molecular Formula: C9H10O
Molecular Weight: 134.175100 [g/mol]
HAZARDS IDENTIFICATIONEMERGENCY OVERVIEW
Potential Health Effects
May cause eye irritation.
May cause skin irritation.
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. The toxicological properties of this substance have not
been fully investigated.
May cause respiratory tract irritation. The toxicological properties
of this substance have not been fully investigated.
No information found.
FIRST AID MEASURES
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
Flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Get medical aid if
irritation develops or persists.
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
FIRE FIGHTING MEASURES
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
In case of fire, use water, dry chemical, chemical foam, or
ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Clean up spills immediately,
observing precautions in the Protective Equipment section. Scoop up
with a nonsparking tool, then place into a suitable container for
HANDLING and STORAGE
Wash thoroughly after handling. Wash hands before eating. Remove
contaminated clothing and wash before reuse. Use only in a
well-ventilated area. Avoid contact with eyes, skin, and clothing.
Keep away from heat, sparks and flame. Avoid ingestion and
Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Store in a cool, dry place. Keep container closed when not
The Reductive Amination of Benzyl Methyl Ketone
Benzyl methyl ketone can react with ammonia in the
in which [a]: Raney Nickel, Pt, H2, Al powder in
the presence of HgCl2, Nickel plated Zinc; [b]: 20-170°C, 1-130 atm,
Reaction conditions can differ widely. (Only low
pressure and low temperature aminations have been encountered so far
in the Netherlands.)
The Oxime Route
Benzyl methyl ketone reacts with hydroxylamine to
give the oxime, which can be hydrogenated to give the amphetamine:
in which [a]: Na (amalgamated), Na (absolute
ethanol), LiAlH4, or H2 and Raney Nickel, nickel, iron, nickel
plated zinc; [b]: 20-170°C, 1-130 atm;
Electrolytical reduction has also been reported.
Great differences have been described for the reaction conditions.
The Phenylnitropropene Route
Condensation of benzaldehyde with nitroethane
yields 1-phenyl-2-nitropropene. Hydrogenation of the double bond and
subsequent reduction of the nitro group gives the amphetamine:
in which [a]: LiAlH4, H2 and Raney Nickel or Pd/C;
[b]: 20-100°C, 1-80 atm, CH3OH, C2H5OH, H2O/HCOOH, C2H5OH.
These API/ chemicals are designated as those that are used in
the manufacture of the controlled substances and are important to
the manufacture of the substances. For any (Control Substance)
products Import and Export *** subjected to your country government
laws /control substance ACT.
Note /Government Notification: N/A