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HOME >> API >> API List 2 >> Granisetron Hcl >> Dosage

DOSAGE
Granisetron Hcl CAS Number 107007-99-8

Granisetron comes as a tablet and a solution (liquid) to take by mouth. Granisetron may be taken with or without food. When taken to prevent nausea and vomiting caused by chemotherapy, the first dose of Granisetron usually is taken 1 hour before chemotherapy is begunWhen taken to prevent nausea and vomiting caused by radiation, Granisetron is usually taken within 1 hour before treatment. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Granisetron exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Granisetron injections are given by qualified health care professionals.

Chemotherapy-Induced Nausea and Vomiting
Adults

IV 10 mcg/kg (commonly rounded to nearest 1 mg), given up to 30 min before starting chemotherapy. Give only on day(s) of chemotherapy.
Chemotherapy-Induced Nausea and Vomiting
Adults

PO 1 mg twice daily. Give the first oral dose up to 1 h before chemotherapy and the second dose 12ߣh later. Give granisetron only on day(s) of chemotherapy. Alternately, a single 2 mg dose may be given up to 1 h before chemotherapy.
Children

IV 10 mcg/kg, given up to 30 min before starting chemotherapy. Give only on day(s) of chemotherapy.
Radiation-Induced Nausea and Vomiting
Adults

PO 2 mg once daily. Give the dose up to 1 h before radiation therapy. Give granisetron only on day(s) of radiation therapy.
Prevention/Treatment Postoperative Nausea and Vomiting
Adults

IV For prevention, use 1 mg undiluted, administered over 30 seconds, before induction of anesthesia or immediately before reversal of anesthesia. For treatment, use 1 mg undiluted, administered over 30 seconds, after surgery.

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