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HOME >> API >> API List 2 >> Netaglinide >> Drug Description

DRUG DESCRIPTION
Netaglinide CAS Registry Number 105816-04-4

Netaglinide is an oral medium-to-long acting anti-diabetic drug from the sulfonylurea class. It is classified as a second generation sulfonylurea, which means that it undergoes enterohepatic circulation.Mechanism of action is produced by blocking potassium channels in the beta cells of the islets of langerhans. By partially blocking the potassium channels, it will increase the time the cell spends in the calcium release stage of cell signaling leading to an increase in calcium. The increase in calcium will initiate more insulin release from each beta cell.

Netaglinide is used to treat type 2 diabetes along with diet, exercise, and insulin therapy, if necessary.

Netaglinide may also be used for purposes other than those listed in this medication guide.

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