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HOME >> API >> API List 2 >> Netaglinide >> Precautions

PRECAUTIONS
Netaglinide CAS Registry Number 105816-04-4

There have been no clinical studies establishing conclusive evidence of macrovascular risk reduction with Netaglinide or any other anti-diabetic drug.The metabolism and excretion of Netaglinide may be slowed in patients with impaired renal and/or hepatic function. If hypoglycemia should occur in such patients, it may be prolonged and appropriate management should be instituted.In initiating treatment for type 2 diabetes, diet should be emphasized as the primary form of treatment. Caloric restriction and weight loss are essential in the obese diabetic patient. Proper dietary management alone may be effective in controlling the blood glucose and symptoms of hyperglycemia. The importance of regular physical activity should also be stressed, and cardiovascular risk factors should be identified and corrective measures taken where possible. Use of Netaglinide or other antidiabetic medications must be viewed by both the physician and patient as a treatment in addition to diet and not as a substitution or as a convenient mechanism for avoiding dietary restraint. Furthermore, loss of blood glucose control on diet alone may be transient, thus requiring only short- term administration of Netaglinide or other antidiabetic medications. Maintenance or discontinuation of Netaglinide or other antidiabetic medications should be based on clinical judgment using regular clinical and laboratory evaluations.

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