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Pentoxifylline
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CONSUMER INFORMATION
Pentoxifylline
CAS NO 6493-05-6
USES: This medication is used to improve the symptoms of a certain
blood flow problem in the legs/arms (intermittent claudication due to
occlusive artery disease). Pentoxifylline can decrease the muscle
aching/pain/cramps with exercise, including walking, that occur with
intermittent claudication. Pentoxifylline belongs to a class of drugs known
as hemorrheologic agents. It works by helping blood flow more easily through
narrowed arteries. This increases the amount of oxygen that can be delivered
by the blood when the muscles need more (e.g., during exercise).
HOW TO USE: Dosage is based on your medical condition, kidney
function, and response to therapy.
Use this medication regularly in order to get the most benefit from it. To
help you remember, take it at the same times each day. It is important to
continue taking this medication even if you feel well. Do not stop this
medication without your doctor's permission. Improvement in symptoms can
occur in 2-4 weeks, but it may take up to 8 weeks to get the full benefit.
SIDE EFFECTS: Nausea, vomiting, gas, belching, and dizziness may
occur. If any of these effects persist or worsen, notify your doctor or
pharmacist promptly. Tell your doctor immediately if any of these rare but
very serious side effects occur: unusual sweating, fast/irregular heartbeat,
fainting, new/severe tiredness, weakness, bluish fingernails/lips, pale
skin, cough, loss of appetite, weight loss, new diarrhea, signs of infection
(e.g., fever, chills, persistent sore throat), persistent nausea,
stomach/abdominal pain, dark urine, yellowing eyes/skin, easy
bruising/bleeding. A very serious allergic reaction to this drug is
unlikely, but seek immediate medical attention if it occurs. Symptoms of a
serious allergic reaction may include: rash, itching, swelling, severe
dizziness, trouble breathing.
PRECAUTIONS: Before taking pentoxifylline, tell your doctor or
pharmacist if you are allergic to it; or to caffeine, theophylline, or
theobromine; or if you have any other allergie Before using this medication,
tell your doctor or pharmacist your medical history, especially of: kidney
problems, chest pain (angina), heart rhythm problems, recent major surgery,
stomach ulcer, problems with the retina (e.g., retinopathy due to HIV or
diabetes). Kidney function declines as you grow older. This medication is
removed by the kidneys. Therefore, caution is advised when using this drug
in the elderly because they may be more sensitive to the effects of the
drug, especially dizziness.
MISSED DOSE: If you miss a dose, take it as soon as you remember
unless it is within 2 hours of your next dose. In that case, skip the missed
dose and resume your usual dosing schedule. Do not double the dose to catch
up
STORAGE: Store tablets at room temperature between 59-86 degrees F
(15-30 degrees C) away from light and moisture. Do not store in the
bathroom. Keep all medicines away from children
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