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buprofen belongs to a class of drugs called non-steroidal anti-inflammatory drugs

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HOME >> Pharmaceuticals API List 1 >> Ibuprofen >> Interaction

Ibuprofen CAS number 15687-27-1

INTERACTION
Ibuprofen CAS number 15687-27-1

Ibuprofen is associated with several suspected or probable interactions that can affect the action of other drugs. Ibuprofen may increase the blood levels of lithium (Establish) by reducing the excretion of lithium by the kidneys. Increased levels of lithium may lead to lithium toxicity. Ibuprofen may reduce the blood pressure-lowering effects of drugs that are given to reduce blood pressure. This may occur because prostaglandins play a role in the regulation of blood pressure. When ibuprofen is used in combination with aminoglycosides [for example, gentamicin (Garamycin)] the blood levels of the aminoglycoside may increase, presumably because the elimination of aminoglycosides from the body is reduced. This may lead to aminoglycoside-related side effects. Individuals taking oral blood thinners or anticoagulants [for example, warfarin (Coumadin)] should avoid ibuprofen because ibuprofen also thins the blood, and excessive blood thinning may lead to bleeding.

Before taking ibuprofen, tell your doctor if you are taking any of the following drugs:

*aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as diclofenac (Voltaren), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin , ketoprofen , ketorolac , mefenamic acid , meloxicam , nabumetone , naproxen (, piroxicam , and others;
*an ACE inhibitor such as benazepril , captopril , fosinopril , enalapril , lisinopril , moexipril , perindopril , quinapril (Accupril), ramipril (, or trandolapril
*lithium
*diuretics (water pills) such as furosemide
*methotrexate
*steroids  or
*a blood thinner such as warfarin

Information Associated with Product:
DRUG DESCRIPTION
DOSAGE
SIDE EFFECTS
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Ibuprofen

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