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HOME >> Pharmaceuticals API List 2 >> Levetiracetam >> Drug Description

Levetiracetam CAS NO. 102767-28-2

DRUG DESCRIPTION
Levetiracetam CAS NO. 102767-28-2

Levetiracetam is an anticonvulsant medication used to treat epilepsyIt is S- enantiomer of etiracetam, structurally similar to the prototypical nootropic drug piracetam.

Properties
Molecular formula C8H14N2O2
Molar mass 170.21 g mol−1
Appearance Fine white crystalline powder
Pharmacology
Bioavailability 100%
Routes of
administration Oral, Intravenous
Elimination
half-life 6 - 8 hr
Excretion Urinary

The chemical name of levetiracetam, a single enantiomer, is (-)-(S)-α-ethyl-2-oxo-1-pyrrolidine acetamide, its molecular formula is C8H14N2O2 and its molecular weight is 170.21.Levetiracetam is a white to off-white crystalline powder with a faint odor and a bitter taste. It is very soluble in water (104.0 g/100 mL). It is freely soluble in chloroform (65.3 g/100 mL) and in methanol (53.6 g/100 mL), soluble in ethanol (16.5 g/100 mL), sparingly soluble in acetonitrile (5.7 g/100 mL) and practically insoluble in n-hexane. (Solubility limits are expressed as g/100 mL solvent.)

Levetiracetam tablets contain the labeled amount of levetiracetam. Inactive ingredients: colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, polyethylene glycol 3350, polyethylene glycol 6000, polyvinyl alcohol, talc, titanium dioxide, and additional agentsLevetiracetam oral solution contains 100 mg of levetiracetam per mL. Inactive ingredients: ammonium glycyrrhizinate, citric acid monohydrate, glycerin, maltitol solution, methylparaben, potassium acesulfame, propylparaben, purified water, sodium citrate dihydrate and natural and artificial flavor.

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