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Paroxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant.

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HOME >> Pharmaceuticals API List 2 >> Paroxetine

Paroxetine  CAS number 61869-08-7
 
Paroxetine pdf api
CAS number 61869-08-7

Paroxetine Formula C19H20FNO3
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant.

Paroxetine is primarily used to treat the symptoms of major depression, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), panic disorder, generalized anxiety disorder (GAD), social phobia/social anxiety disorder, and premenstrual dysphoric disorder (PMDD).

Systematic (IUPAC) name
(3S,4R)- 3-([benzo[d] [1,3]dioxol-5-yloxy] methyl)- 4-(4-fluorophenyl) piperidine
Identifiers

ATC code N06AB05
PubChem 43815
DrugBank APRD00364
ChemSpider 39888
Chemical data
Formula C19H20FNO3
Mol. mass 329.3
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability Completely absorbed from GI, but extensive first-pass metabolism in the liver; Tmax 4.9 (with meals) to 6.4 hours (fasting)
Protein binding 93–95%
Metabolism Extensive, hepatic (mostly CYP2D6-mediated)
Half life 24 hours (range 3–65 hours)
Excretion 64% in urine, 36% in bile
Therapeutic considerations
License data
Pregnancy cat.
Legal status
Prescription only
Routes Oral

Information Associated with Product:
DRUG DESCRIPTION
DOSAGE
SIDE EFFECTS
PRECAUTIONS
INTERACTION
CONSUMER INFORMATION
 
 
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Paroxetine

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