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HOME >> Pharmaceuticals API List 2 >> Loratadine >> Side Effects

SIDE EFFECTS
Loratadine CAS number 79794-75-5

Headache, fatigue, dry mouth, thirst, dry nose or hoarseness may occur. These effects should lessen as your body adjusts to the medication. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Tell your doctor immediately if any of these unlikely but serious side effects occur: nervousness, rapid or pounding heartbeat, unusual weakness, stomach pain, dizziness, diarrhea, wheezing, increased physical activity. Loratadine does not usually cause drowsiness when used at recommended doses and under normal circumstances. However, be sure of the drug's effects before engaging in activities that require alertness such as driving or using machinery. A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Non-sedating antihistamine

As a non-sedating antihistamine, loratadine causes less sedation and psychomotor impairment than the older antihistamines because it penetrates the blood brain barrier only to a slight extent.

Although drowsiness is rare, patients should nevertheless be advised that it can occur and may affect performance of skilled tasks (e.g. driving); excess alcohol should be avoided.

Most common side-effects

Drowsiness, headache, psychomotor impairment, and antimuscarinic effects such as urinary retention, dry mouth, blurred vision, and gastrointestinal disturbances are the most common side effects.

Other rarer side-effects

Hypotension, extrapyramidal effects, dizziness, confusion, depression, sleep disturbances, lower back pain, tremor, convulsions, palpitation, arrhythmias, hypersensitivity reactions (including bronchospasm, angioedema, and anaphylaxis, rashes, and photosensitivity reactions), blood disorders, liver dysfunction, and angle-closure glaucoma are less common side effects.

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