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HOME >> API >> API List 3 >> Ondansetron Base >> Consumer Information

CONSUMER INFORMATION
Ondansetron Base CAS number 116002-70-1

USES: This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer chemotherapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's natural substances (serotonin) that causes vomiting.

HOW TO USE: Before using, check this product visually for discoloration. Ondansetron injection should be clear and colorless. If discoloration is present, do not use the liquid. When the vial is stored upright after first use, clumps may occasionally form on the top of the vial. Check the vial and the vial top carefully for particles. If particles are present, shake the vial to re-dissolve the particles. If any particles remain after the vial is shaken, do not use the liquid. Follow all instructions for proper mixing with the correct IV fluids. If you have any questions about the use of this medication, consult your pharmacist. To prevent nausea from chemotherapy, ondansetron may be given as a single dose or 3 smaller doses. It is mixed in a solution and given into a vein (IV) by a health care professional, usually over 15 minutes or as directed by your doctor. This drug is usually started 30 minutes before your chemotherapy treatment begins. Do not give this medication any faster than recommended because this may increase the chance of serious side effects such as blurred vision or slowed/irregular heartbeat. Depending on the type of chemotherapy treatment you are receiving, a smaller first dose may be used, and a second and third dose may be given 4 and 8 hours after your first dose. You may also be switched to a medication you can take by mouth, or a low dose of ondansetron may be given continuously through an IV for up to 24 hours.

SIDE EFFECTS: Headache, fever, lightheadedness, dizziness, drowsiness, tiredness, constipation, or redness/pain/burning at the injection site may occur. If these effects persist or worsen, notify your doctor promptly.

PRECAUTIONS: Before using ondansetron, tell your doctor or pharmacist if you are allergic to it; or to other serotonin blockers (e.g., granisetron); or if you have any other allergies.Infants younger than 5 months may be more sensitive to the effects of this drug, especially diarrhea. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

MISSED DOSE: It is important that the dose be given before cancer chemotherapy as directed. If you miss a dose, contact your doctor or pharmacist to establish a new dose schedule. If you are using this medication on a regular schedule and you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Different brands/packaging of this medication may have different storage requirements. Read the package labeling or ask your pharmacist for the storage requirements for the product you are using. Protect from light. Do not freeze. Discard the medication if it has been frozen.

After mixing with the proper IV fluid, the solution should be discarded after 24 hours if stored at room temperature and 48 hours if refrigerated.

Information Associated with Product:
DRUG DESCRIPTION DOSAGE SIDE EFFECTS PRECAUTIONS INTERACTION CONSUMER INFORMATION >>
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