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Moxifloxacin HCl CAS No.: 186826-86-8
WARNING: This medication may rarely cause tendon damage (e.g.,
tendinitis, tendon rupture) during or after treatment. Your risk for tendon
problems is greater if you are over 60 years of age, if you are taking
corticosteroids (such as prednisone), or if you have had a kidney, heart or
lung transplant. Stop exercising, rest, and seek immediate medical attention
if you develop joint/muscle/tendon pain or swelling.
USES: Moxifloxacin is used to treat a variety of bacterial
infections. This medication belongs to a class of drugs called quinolone
antibiotics. It works by stopping the growth of bacteria.
This antibiotic treats only bacterial infections. It will not work for virus
infections (e.g., common cold, flu). Unnecessary use or overuse of any
antibiotic can lead to its decreased effectiveness.
HOW TO USE: Take this medication by mouth with or without food,
usually once daily or as directed by your doctor. The dosage and length of
treatment is based on your medical condition and response to treatment.
Drink plenty of fluids while taking this drug unless your doctor tells you
Take this medication at least 4 hours before or 8 hours after taking any
drugs that contain magnesium or aluminum. Some examples include quinapril,
certain forms of didanosine (chewable/dispersible buffered tablets or
pediatric oral solution), vitamins/minerals, and antacids. Follow the same
instructions if you take bismuth subsalicylate, sucralfate, iron, and zinc.
These medications bind with moxifloxacin and prevent its full absorption.
Antibiotics work best when the amount of medicine in your body is kept at a
constant level. It is important not to miss a dose. To help you remember,
take this medication at the same time every day.
SIDE EFFECTS: Nausea, diarrhea, dizziness, lightheadedness, headache,
weakness, or trouble sleeping may occur. If any of these effects persist or
worsen, tell your doctor or pharmacist promptly. Tell your doctor
immediately if any of these unlikely but serious side effects occur:
mental/mood changes (e.g., anxiety, confusion, hallucinations, depression,
rare thoughts of suicide), shaking (tremors). Moxifloxacin may rarely cause
serious nerve problems that may be reversible if identified and treated
early. Seek immediate medical attention if you develop any of the following
symptoms: pain/numbness/burning/tingling/weakness in any part of the body,
changes in how you sense touch/pain/temperature/body position/vibration.
This medication may rarely cause a severe intestinal condition (pseudomembranous
colitis) due to a type of resistant bacteria. This condition may occur
during treatment or weeks to months after treatment has stopped. Do not use
anti-diarrhea products or narcotic pain medications if you have any of the
following symptoms because these products may make them worse. Tell your
doctor immediately if you develop: persistent diarrhea, abdominal or stomach
pain/cramping, blood/mucus in your stool. Use of this medication for
prolonged or repeated periods may result in oral thrush or a new vaginal
yeast infection. Contact your doctor if you notice white patches in your
mouth, a change in vaginal discharge, or other new symptoms. A very serious
allergic reaction to this drug is rare. However, seek immediate medical
attention if you notice any of the following symptoms of a serious allergic
reaction: rash, itching/swelling, severe dizziness, trouble breathing.
PRECAUTIONS: Before taking moxifloxacin, tell your doctor or
pharmacist if you are allergic to it; or to other quinolone antibiotics
(e.g., ciprofloxacin, levofloxacin); or if you have any other allergies.
This medication should not be used if you have certain medical conditions.
Before using this medicine, consult your doctor or pharmacist if you have:
history of a certain heart problem (QT prolongation in the EKG), untreated
low levels of potassium or magnesium in the blood.
Before using this medication, tell your doctor or pharmacist your medical
history, especially of: diabetes, family history of a certain heart problem
(QT prolongation in the EKG), heart problems (e.g., slow/fast/irregular
heartbeat, heart failure, recent heart attack), joint/tendon problems (e.g.,
tendonitis, bursitis), liver disease, nervous system disorder (e.g.,
peripheral neuropathy), seizure disorder, conditions that increase your risk
of seizures (e.g., brain/head injury, brain tumors, cerebral
his drug may make you dizzy or lightheaded. Use caution while driving, using
machinery, or taking part in any activity that requires alertness. Limit
This medication may make you more sensitive to the sun. Avoid prolonged sun
exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective
clothing when outdoors.
Caution is advised when using this drug in children because they may be more
sensitive to its possible side effects (e.g., joint/tendon problems).
Discuss the risks and benefits with the doctor.
Older adults may be more sensitive to the side effects of this medication
such as heart problems or tendon problems. The risk for tendon problems is
higher if they are also taking corticosteroids (e.g., prednisone,
MISSED DOSE: If you miss a dose, take it as soon as you remember. If
it is near the time of the next dose, skip the missed dose and resume your
usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store at room temperature at 77 degrees F (25 degrees C)
away from light and moisture. Brief storage between 59-86 degrees F (15-30
degrees C) is permitted. Do not store in the bathroom. Keep all medicines
away from children and pets.