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HOME >> Pharmaceuticals API List 3 >> Risperidone

Risperidone cas no.106266-06-2

Risperidone
CAS number 106266-06-2

Structure :

Systematic (IUPAC) name
4-[2-[4-(6-fluorobenzo[d]isoxazol-3-yl)-
1-piperidyl]ethyl]-3-methyl-
2,6-diazabicyclo[4.4.0]deca-1,3-dien-5-one
Identifiers
CAS number 106266-06-2
ATC code N05AX08
PubChem 5073
DrugBank APRD00187
Chemical data
Formula C23H27FN4O2
Mol. mass 410.485 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability 70% (oral)
Metabolism Hepatic (CYP2D6-mediated)
Half life 3–20 hours
Excretion Urinary
Therapeutic considerations
Pregnancy cat. C
Legal status Prescription only
Routes Oral and extended-release intramuscular injection

Risperidon is an atypical antipsychotic used to treat adolescent schizophrenia, the mixed and manic states associated with bipolar disorder, and irritability in children with autism.

Risperidone, a psychotropic agent belonging to the chemical class of benzisoxazole derivatives. The chemical designation is 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one. Its molecular formula is C23H27FN4O2 and its molecular weight is 410.49.Risperidone is a white to slightly beige powder. It is practically insoluble in water, freely soluble in methylene chloride, and soluble in methanol and 0.1 N HCl.

Risperidon Tablets are available in 0.25 mg , 0.5 mg , 1 mg (white), 2 mg , 3 mg , and 4 mg (green) strengths. Risperidon tablets contain the following inactive ingredients: colloidal silicon dioxide, hypromellose, lactose, magnesium stearate, microcrystalline cellulose, propylene glycol, sodium lauryl sulfate, corn.

The 0.25 mg, 0.5 mg, 2 mg, 3 mg, and 4 mg tablets also contain talc and titanium dioxide. The 0.25 mg tablets contain yellow iron oxide; the 0.5 mg tablets contain red iron oxide.

Risperidon is also available as a 1 mg/mL oral solution. Risperidon Oral Solution contains the following inactive ingredients: tartaric acid, benzoic acid, sodium hydroxide, and purified water.

Information Associated with Product:

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