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HOME >> Pharmaceuticals API List 3 >> Venlafaxine

Venlafaxine CAS number 93413-69-5

Venlafaxine

CAS number 93413-69-5

Formula Structure :

Systematic (IUPAC) name
1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]cyclohexanol

Identifiers
CAS number 93413-69-5
ATC code N06AX16
PubChem 5656
DrugBank APRD00125
ChemSpider 56641

Chemical data
Formula C17H27NO2
Mol. mass 277.402 g/mol
SMILES eMolecules & PubChem

Pharmacokinetic data
Bioavailability 45%
Protein binding 27%
Metabolism Hepatic
Half life 5 ± 2 hours (parent compound); 11 ± 2 hours (active metabolite)
Excretion Renal

Venlafaxine is an extended-release capsule for oral administration that contains venlafaxine hydrochloride, a structurally novel antidepressant. It is designated (R/S)-1-[2-(dimethylamino)-1- (4-methoxyphenyl)ethyl] cyclohexanol hydrochloride or (±)-1-[α- [(dimethylamino)methyl]-pmethoxybenzyl] cyclohexanol hydrochloride and has the empirical formula of C17H27NO2 HCl.

Its molecular weight is 313.87.Venlafaxine hydrochloride is a white to off-white crystalline solid with a solubility of 572 mg/mL in water (adjusted to ionic strength of 0.2 M with sodium chloride).

Its octanol : water (0.2 M sodium chloride) partition coefficient is 0.43.

Information Associated with Product:

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