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HOME >> Pharmaceuticals API List 4 >> Ceftizoxime Sodium


 

Ceftizoxime Sodium
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CAS Registry Number 68401-82-1



Synonyms (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt

Molecular Structure Ceftizoxime sodium, (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt, CAS #: 68401-82-1
Molecular Formula C13H12N5NaO5S2
Molecular Weight 405.38
CAS Registry Number 68401-82-1

ceftizoxime, an antibiotic, to help treat your infection. The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 30 minutes, two or three times a day.

Ceftizoxime eliminates bacteria that cause many kinds of infections, including lung, skin, bone, joint, stomach, blood, and urinary tract infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.


a third-generation cephalosporin antibiotic.
indications It is prescribed in the treatment of infections caused by susceptible bacterial strains (does not include Pseudomonas aeruginosa), primarily in the respiratory system, genitourinary system, bone, joints, and skin.
contraindications Known sensitivity to this drug prohibits its use. It is used with caution in patients who are allergic to penicillin.

Side effects Return to top

Ceftizoxime may cause side effects. If you are administering ceftizoxime into a muscle, it may be mixed with lidocaine (Xylocaine) to reduce pain at the injection site. Tell your health care provider if any of these symptoms are severe or do not go away:

* diarrhea
* stomach pain
* upset stomach
* vomiting

If you experience any of the following symptoms, call your health care provider immediately:

* unusual bleeding or bruising
* difficulty breathing
* itching
* rash
* hives
* sore mouth or throat

Dosage and Administration
Adults

IV/IM 1 to 2 g every 8 to 12 h (life-threatening infections: IV up to 2 g every 4 h or 3 to 4 g every 8 h).
Children older than 6 mo of age

IV/IM 50 mg/kg every 6 to 8 h up to 200 mg/kg/day (max, 12 g/day).

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