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HOME >> API >> API List1 >> Alendronate sodium >> Drug Description

Alendronate sodium Ph. Eur. CAS Registry Number: 121268-17-5




Alendronate sodium (121268-17-5)
DRUG DESCRIPTION

A drug used to treat certain bone conditions, such as osteoporosis and Paget disease of the bone. It is also being studied in the treatment of hypercalcemia (high levels of calcium in the blood) and bone pain caused by cancer. Alendronate sodium slows the breakdown of bone and prevents the loss of calcium. It is a type of bisphosphonate.

alendronate sodium is a bisphosphonate that acts as a specific inhibitor of osteoclast-mediated bone resorption. Bisphosphonates are synthetic analogs of pyrophosphate that bind to the hydroxyapatite found in bone.

Alendronate sodium is chemically described as (4-amino-1-hydroxybutylidene) bisphosphonic acid monosodium salt trihydrate.

The empirical formula of alendronate sodium is C4H12NNaO7P2•3H2O and its formula weight is 325.12.

Alendronate sodium is a white, crystalline, nonhygroscopic powder. It is soluble in water, very slightly soluble in alcohol, and practically insoluble in chloroform.

 

   
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