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taj pharma api calcitonin

HOME >> API >> API List1 >> Calcitonin >> Overdose

OVERDOSE
Calcitonin CAS No. 47931-85-1

No instances of overdose withSpray have been reported and no serious adverse reactions have been associated with high doses. There is no known potential for drug abuse for calcitonin-salmon.Single doses

Spray up to 1600 I.U., doses up to 800 I.U. per day for three days and chronic administration of doses up to 600 I.U. per day have been studied without serious adverse effects. A dose of 1000 I.U. of MiacalcinÒ injectable solution given subcutaneously may produce nausea and vomiting. A dose of MiacalcinÒ injectable solution of 32 I.U. per kg per day for one or two days demonstrated no additional adverse effects.

There have been no reports of hypocalcemic tetany. However, the pharmacologic actions of MiacalcinÒ Nasal Spray suggest that this could occur in overdose. Therefore, provisions for parenteral administration of calcium should be available for the treatment of overdose.

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