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HOME >> API >> API List1 >> Capecitabine >> Dosage

DOSAGE
Capecitabine CAS No. 154361-50-9

Your doctor may want you to take a combination of 500mg and 150mg tablets. You need to make sure that you are taking the right dose.

The tablets should be swallowed whole with a glass of water, within half an hour of the end of a meal, as capecitabine works best if it is broken down in the stomach with food. You should take them in the morning after breakfast, and then again after your evening meal, so that the doses are spaced at least eight hours apart.

If you have trouble swallowing capecitabine tablets, they can be dissolved in a 200ml glass of warm water. The mixture should be stirred with a spoon until the tablets are completely dissolved and drunk immediately. The glass and spoon should be washed and kept separate from your other crockery and cooking utensils.

Capecitabine tablets are usually taken for a number of days, followed by a rest period in which no tablets are taken. This can vary depending upon the type of cancer you have. It is important to follow the instructions carefully and take the tablets as directed by your doctor, nurse or pharmacist.

You should only get the tablets from your hospital. You can't get a repeat prescription from your GP.

* For mild renal dysfunction (creatinine clearance 30-50 mL/min), it is recommended to reduce dose by 25%.
* For severe renal dysfunction (creatinine clearance <30 mL/min), treatment is not recommended.
* There is no recommendation for hepatic dysfunction.
* For elderly patients, lower doses may be required due to higher incidences of serious adverse reactions.

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