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HOME >> API >> API List1 >> Clonazepam >> Drug Description

CAS Number 1622-61-3

Clonazepam CAS Number 1622-61-3

Clonazepam belongs to a group of drugs called benzodiazepines. Benzodiazepines are sedative-hypnotic drugs that help to relieve nervousness, tension, anxiety symptoms, and seizures by slowing the central nervous system. To do this, they block the effects of a specific chemical involved in the transmission of nerve impulses in the brain, decreasing the excitement level of the nerve cells.

When clonazepam is used to treat panic disorder, it is more sedating than alprazolam, another benzodiazepine drug used to treat panic disorder. However, unlike alprazolam, clonazepam may trigger depressive episodes in patients with a previous history of depression. In people who experience social phobia, treatment with clonazepam reduces the rate of depression. The use of clonazepam for social phobia is considered off-label use—a use that is legal, but not specifically approved by the FDA.

Clonazepam comes in 0.5 mg-, 1 mg-, and 2 mg tablets.

Clonazepam comes as a tablet to take by mouth. It usually is taken three times a day and may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take clonazepam exactly as directed.

Clonazepam can be habit-forming. Do not take a larger dose, take it more often, or for a longer time than your doctor tells you to. Tolerance may develop with long-term or excessive use, making the drug less effective. This medication must be taken regularly to be effective. Do not skip doses even if you feel that you do not need them. Do not take clonazepam for more than 4 months or stop taking this medication without talking to your doctor. Stopping the drug suddenly can worsen your condition and cause withdrawal symptoms (anxiousness, sleeplessness, and irritability). Your doctor probably will decrease your dose gradually.
Clonazepam is also used to treat symptoms of Parkinson's disease, twitching, schizophrenia, and for pain management. Talk to your doctor about the possible risks of using this drug for your condition.

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