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HOME >> API >> API List1 >> Entacapone >> Drug Description

DRUG DESCRIPTION
Entacapone CAS Number 130929-57-6

Entacaponeis a prescription medication used to treat Parkinson's disease. It is always used in combination with carbidopa-levodopa products as it does not have any activity for treating Parkinson's disease when used without levodopa. Entacapone is useful for people who experience "wearing off" of their carbidopa-levodopa before each dose.

Entacapone is a member of the class of drugs known as nitrocatechols.

Entacapone is an inhibitor of catechol-O-methyltransferase (COMT), used in the treatment of Parkinson's Disease as an adjunct to levodopa/carbidopa therapy. It is a nitrocatechol-structured compound with a relative molecular mass of 305.29. The chemical name of entacapone is (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide.

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