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HOME >> Pharmaceuticals API List 4 >> Betalactams Piperacillin >> Interaction

INTERACTION
Betalactams Piperacillin

Increased effect: Probenecid may decrease cephalosporin elimination; may cause prolongation of PT/INR in patients receiving warfarin

Increased toxicity: Furosemide, aminoglycosides may be a possible additive to nephrotoxicity.

Ethanol/Nutrition/Herb Interactions:

Food: Administration with food decreases and delays the peak plasma concentration.

Aminoglycosides: Penicillins may decrease the serum concentration of Aminoglycosides. Primarily associated with extended spectrum penicillins, and patients with renal dysfunction.

Fusidic Acid: May diminish the therapeutic effect of Penicillins.

Methotrexate: Penicillins may decrease the excretion of Methotrexate. Risk C: Monitor therapy

Tetracycline Derivatives: May diminish the therapeutic effect of Penicillins.

Information Associated with Product:

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Ceftizoxime Sodium	Cefotaxime Sodium	Cefuroxime Sodium	Cefixime	Cefalexin	Betalactams Piperacillin	Meropenem	Tazobactam
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