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Rabeprazole sodium blocks acid production in the stomach

HOME >> Pharmaceuticals API List 3 >> Rabeprazole Sodium >> Dosage

DOSAGE
Rabeprazole Sodium CAS Number 117976-89-3

Take Rabeprazole sodium once a day, with or without food. Swallow the tablet whole; it should not be crushed, chewed, or split. You can continue taking antacids during Rabeprazole sodium therapy.

If you're using Rabeprazole sodium along with amoxicillin and clarithromycin, take all three drugs at the same time twice a day, once in the morning and again in the evening. This three-drug regimen should be taken with meals.

For healing ulcerative or erosive GERD, the recommended dose for adults is 20 mg daily for 4-8 weeks. If healing does not occur after 8 weeks, another 8 week course may be considered. The recommended maintenance dose is 20 mg daily. Heartburn due to GERD is treated with 20 mg daily for 4 weeks and an additional 4 weeks if symptoms do not resolve. Ulcers are treated with 20 mg daily for 4 weeks. For the management of Zollinger-Ellison Syndrome, the starting dose for adults is 60 mg daily, and the dose is adjusted based on improvement in symptoms, healing of ulcers, or the effectiveness of acid suppression. Doses of 100 mg per day and 60 mg twice daily have been used in some patients with Zollinger-Ellison Syndrome. The regimen for eradication of Helicobacter pylori is rabeprazole 20 mg given twice daily (morning and evening) for 7 days.

Tablets should be swallowed whole and should not be crushed, split or chewed. Rabeprazole can be taken with or without meals since food has little effect on its absorption.

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