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valsartan

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HOME >> Pharmaceuticals API List >> Pharmaceuticals API List 3 >> Valsartan

valsartan CAS number 137862-53-4

Valsartan pdf api

CAS number 137862-53-4

Formula Structure :
Valsartan Formula C24H29N5O3
Systematic (IUPAC) name
(2S)-3-methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid

Identifiers
CAS number 137862-53-4
ATC code C09CA03
PubChem 60846
DrugBank APRD00133

Chemical data
Formula C24H29N5O3
Mol. mass 435.519 g/mol
SMILES eMolecules & PubChem

Pharmacokinetic data
Bioavailability 25%
Protein binding 95%
Metabolism
Half life 6 hours
Excretion Renal 30%, biliary 70%

Valsartan is a nonpeptide, orally active, and specific angiotensin II antagonist acting on the AT1 receptor subtype.

Valsartan is chemically described as N-(1-oxopentyl)-N-[[2′-(1H-tetrazol-5-yl) [1,1′-biphenyl]-4-yl]methyl]-L-valine. Its empirical formula is C24H29N5O3, its molecular weight is 435.5.

Valsartan is a white to practically white fine powder. It is soluble in ethanol and methanol and slightly soluble in water. Valsartan  is available as tablets for oral administration, containing 40 mg, 80 mg, 160 mg or 320 mg.

Information Associated with Product:
DOSAGE
SIDE EFFECTS
PRECAUTIONS
INTERACTION
CONSUMER INFORMATION
 
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Valsartan

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