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HOME >> Pharmaceuticals API List 3 >> Zolmitriptan

Zolmitriptan CAS number 139264-17-8

Zolmitriptan

CAS number 139264-17-8

Formula Structure :

Systematic (IUPAC) name
(4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one

Identifiers
CAS number 139264-17-8
ATC code N02CC03
PubChem 60857
DrugBank APRD00376

Chemical data
Formula C16H21N3O2
Mol. mass 287.357 g/mol

Pharmacokinetic data
Bioavailability 40% (oral)
Protein binding 25%
Metabolism
Half life 3 hours
Excretion Renal (65%) and fecal (35%)
Therapeutic considerations
Pregnancy cat.
B3(AU) C(US)
Routes Oral, nasal spray

Zolmitriptanis a selective 5-hydroxytryptamine 1B/1D (5-HT1B/1D) receptor agonist. Zolmitriptan is chemically designated as (S)-4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone.

The empirical formula is C16H21N3O2, representing a molecular weight of 287.36. Zolmitriptan is a white to almost white powder that is readily soluble in water. ZOMIG Tablets are available as 2.5 mg (yellow) and 5 mg (pink) film coated tablets for oral administration.

The film coated tablets contain anhydrous lactose NF, microcrystalline cellulose NF, sodium starch glycolate NF, magnesium stearate NF, hydroxypropyl methyl-cellulose USP, titanium dioxide USP, polyethylene glycol 400 NF, yellow iron oxide NF (2.5 mg tablet), red iron oxide NF (5 mg tablet), and polyethylene glycol 8000 NF.

Information Associated with Product:

DOSAGE

SIDE EFFECTS

PRECAUTIONS

INTERACTION

CONSUMER INFORMATION

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