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HOME >> Pharmaceuticals API List 3 >> Venlafaxine >> Interaction

INTERACTION
Venlafaxine CAS number 93413-69-5

This product could result in serious, even fatal, drug interactions. Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine) within 2 weeks before or 7 days after treatment with this medication.

This drug should not be used with the following medications because very serious interactions may occur: weight loss drugs (e.g., sibutramine, phentermine).

If you are currently using any of these medications, tell your doctor before starting venlafaxine. Before using this medication, tell your doctor of all prescription and nonprescription/herbal products you may use, especially of: cimetidine, herbal/natural products (e.g., ayahuasca, St. John's wort), lithium, SSRI antidepressants (e.g., fluoxetine, sertraline), triptan migraine drugs (e.g., sumatriptan, almotriptan), other drugs which can cause bleeding/bruising (e.g., thrombolytic drugs such as TPA, anticoagulants such as heparin or warfarin, antiplatelet drugs including NSAIDs such as ibuprofen).

Tell your doctor if you also take drugs that cause drowsiness such as: antihistamines that cause drowsiness (e.g., diphenhydramine), anti-anxiety drugs (e.g., diazepam), anti-seizure drugs (e.g., carbamazepine), medicine for sleep (e.g., sedatives), muscle relaxants, narcotic pain relievers (e.g., codeine), or psychiatric medicines (e.g., chlorpromazine, thioridazine).

Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products. Low-dose aspirin (usually 81-325 mg per day) for heart attack or stroke prevention should be continued unless your doctor instructs you otherwise. Aspirin is similar to NSAID drugs, and can increase the risk of bleeding in combination with this medication

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