Pharmaceuticals API List 3 >>
CAS number 137234-62-9
USES: Voriconazole is an azole antifungal used to treat a variety of
HOW TO USE: This medicine comes with a Patient Information Leaflet.
Read it carefully. Ask your doctor, nurse, or pharmacist any questions that
you may have about this medicine.
Take this medication by mouth, at least 1 hour before or 1 hour after meals,
usually every 12 hours or as directed by your doctor.
The dosage is based on your medical condition, response to therapy, and
This medication works best when the amount of medicine in your body is kept
at a constant level. Therefore, take this drug at evenly spaced intervals.
Continue to take this medication until the full prescribed amount is
finished. Stopping the medication too early may result in a return of the
SIDE EFFECTS: Nausea/vomiting, diarrhea, and headache may occur. If
any of these effects persist or worsen, notify your doctorserious side
effects occur: vision changes (e.g., blurred vision, color vision changes),
sensitivity of eyes to light (photophobia), bone/muscle/joint pain,
weakness, mental/mood changes, muscle stiffness/spasm, restlessness,
swelling of the ankles/feet, tiredness, easy bleeding/bruising, signs of
infection (e.g., fever, persistent sore throat). Seek immediate medical
attention if any of these rare but very serious side effects occur:
fast/slow/irregular heartbeat, severe dizziness, fainting, change in the
amount of urine, confusion, slurred speech, trouble breathing,
chest/jaw/left arm pain, seizures. Voriconazole may rarely cause serious
(possibly fatal) liver problems. Tell your doctor immediately if any of
these highly unlikely but very serious side effects occur: yellowing
eyes/skin, dark urine, persistent nausea/vomiting, stomach/abdominal pain.
A very serious allergic reaction to this drug is rare. However, seek
immediate medical attention if you notice any of the following symptoms of a
serious allergic reaction: rash, itching, swelling, severe dizziness,
Voriconazole can commonly cause a mild rash that is usually not serious.
However, you may not be able to tell it apart from a rare rash that could be
a sign of a severe allergic reaction. Therefore, seek immediate medical
attention if you develop any rash.
PRECAUTIONS: Before taking voriconazole, tell your doctor or
pharmacist if you are allergic to it; or to other azole antifungalsif you
have any other allergies.
Before using this medication, tell your doctor or pharmacist your medical
history, especially of: liver disease, recent chemotherapy, certain
hereditary problems with digesting/absorbing the sugar galactose (e.g.,
galactose intolerance, Lapp lactase deficiency, glucose-galactose
malabsorption), untreated electrolyte imbalance (e.g., low
potassium/magnesium/calcium levels), heart problems (e.g., irregular
heartbeat, QT prolongation in the EKG, cardiomyopathy).
This drug may cause vision changes. Use caution while driving, using
machinery, or doing any activity that requires clear vision. Do not drive at
Avoid alcoholic beverages since they can increase the risk of serious liver
This medication may make you more sensitive to the sun. Avoid prolonged sun
exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective
clothing when outdoors.
Before having surgery, tell your doctor or dentist that you are using this
MISSED DOSE: If you miss a dose, take it as soon as you remember. If
it is near the time of the next dose, skip the missed dose and resume your
usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store at room temperature between 59-86 degrees F (15-30
degrees C) away from light and moisture. Do not store in the bathroom. Keep
all medicines away from children