Pharmaceuticals API List 3 >>
CAS number 139264-17-8
USES: Zolmitriptan is used to treat migraines. It helps to relieve
headaches, pain, and other symptoms of migraines, including nausea,
vomiting, and sensitivity to light/sound. Prompt treatment allows you to get
back to your normal routine and may decrease your need for other pain
medications. Zolmitriptan does not prevent future migraines or reduce how
often you may get a migraine.
Zolmitriptan belongs to a group of drugs called "triptans." Migraines are
thought to occur when certain blood vessels in the brain become swollen
(dilated). This drug works by helping blood vessels in the brain to return
to normal size. It may also block pain signals in the brain.
HOW TO USE: Read the Patient Information Leaflet available. Your
dosage is based on your medical condition and response to treatment.
Take this medication by mouth, with or without food, at the first sign of a
migraine as directed by your doctor. If there is no improvement in your
symptoms, do not take any more doses of this medication before talking to
your doctor. If your symptoms are only partly relieved, or if your headache
comes back, you may take a second dose after 2 hours or as directed by your
doctor. Do not take more than 10 milligrams in a 24-hour period.
SIDE EFFECTS: Tingling/numbness, nausea, dry mouth, weakness,
drowsiness, or dizziness may occur. If any of these effects persist or
worsen, tell your doctor
Tell your doctor immediately if any of these unlikely but serious side
effects occur: blue fingers/toes/nails, cold feeling in the hands/feet.
Pain/pressure/tightness in the chest/neck/jaw can occur shortly after using
zolmitriptan. These side effects are usually not serious. However, you may
not be able to tell them apart from a rare but very serious reaction related
to a lack of blood flow to the heart, brain, or other parts of the body.
Therefore, seek immediate medical attention if you notice any of these
unlikely side effects: chest/jaw/left arm pain, fainting, irregular/pounding
heartbeat, vision changes, severe nausea, weakness on one side of the body,
confusion, seizures, slurred speech, sudden or severe stomach/abdominal
pain, trouble swallowing, bloody diarrhea.
This medication may rarely cause a very serious condition called serotonin
syndrome. The risk increases when this medication is used with certain other
drugs such as other "triptans" used to treat migraine headaches (e.g.,
sumatriptan, eletriptan), certain antidepressants including SSRIs (e.g.,
citalopram, fluoxetine, paroxetine) and NSRIs (e.g., duloxetine, venlafaxine),
or a certain drug to treat obesity (sibutramine). Before taking this drug,
tell your doctor if you take any of these medications. Serotonin syndrome
may be more likely when you start or increase the dose of any of these
medications. Seek immediate medical attention if you develop some of the
following symptoms: hallucinations, unusual restlessness, loss of
coordination, fast heartbeat, severe dizziness, high fever, severe
nausea/vomiting/diarrhea, twitchy muscles.A very serious allergic reaction
to this drug is rare
PRECAUTIONS: This medication should not be used if you have certain
medical conditions. Before using this medicine, consult your doctor or
pharmacist if you have: heart disease (e.g., chest pain, heart attack,
irregular heartbeat, coronary artery disease, vasospasm), blood flow
problems in the brain (e.g., stroke, transient ischemic attack), blood
vessel disease (e.g., peripheral vascular disease, ischemic bowel disease),
uncontrolled high blood pressure (hypertension), certain types of headaches
(hemiplegic or basilar migraine), severe liver disease.
Before using this medication, tell your doctor or pharmacist your medical
history, especially of: blood circulation disorder (e.g., Raynaud's
disease), kidney disease.
Before using this medication, tell your doctor or pharmacist if you have any
condition that increases your risk of heart disease, including: high
cholesterol level, high blood pressure, diabetes, smoking history, family
history of heart disease or stroke, overweight, female after menopause, male
older than 40 years.
MISSED DOSE: Not applicable.
STORAGE: Store the US product at room temperature between 68-77
degrees F (20-25 degrees C) away from light and moisture.
Store the Canadian product at room temperature between 59-86 degrees F
(15-30 degrees C) away from light and moisture.
Do not store in the bathroom. Keep all medicines away from children.