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Quinine Sulfate

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HOME >> API >> API List 3 >> Quinine Sulfate >> Interaction

Quinine SulfateCAS number 130-95-0
 
INTERACTION
Quinine Sulfate CAS number 130-95-0

Aluminum-containing antacids
Causes delayed or decreased quinine absorption.

Anticoagulants, oral
May cause depression of hepatic enzyme system that synthesizes vitamin K-dependent clotting factors and may enhance action of oral anticoagulants.

Cimetidine
May reduce quinine's Cl and prolong its half-life in body.

Digoxin
May cause increased digoxin serum concentration.

Mefloquine
May cause ECG abnormalities or cardiac arrest and may increase risk of convulsions. Do not use concurrently. Delay administration 12 h after last dose of quinine.

Neuromuscular blocking agents
May potentiate neuromuscular blockade and may result in respiratory difficulties.

Urinary alkalinizers
May increase quinine serum concentrations and potentiate toxicity.

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Quinine Sulfate

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