>> Raspberry Ketone
Raspberry ketone, Oxyphenalon, Frambinone, Rheosmin, Rasketone,
Betuligenol, rasberry ketone, p-Hydroxybenzyl acetone,
Hydroxyphenylbutanone, p-, (p-Hydroxybenzyl)acetone, 2-Butanone,
FEMA No. 2588, WLN: QR D2V1, W258806_ALDRICH, W258814_ALDRICH
CAS Registry Number: 5471-51-2
Molecular Formula: C10H12O2
Molecular Weight: 164.201080 [g/mol]
Water solubility 13 g/L at 25 ºC
Appearance : white crystalline powder
Assay : 98.00 to 100.00 %
Food Chemicals Codex Listed : Yes
Melting point : 82.00 to 84.00 °C. @ 760.00 mm Hg
Boiling point : 200.00 °C. @ 760.00 mm Hg
Flash point : > 200.00 °F. TCC ( > 93.33 °C. )
LogP (o/w) : 0.94
Shelf life : 24.00 month(s) or longer if stored properly.
Storage : store in cool, dry place in tightly sealed
containers, protected from heat and light.
Raspberry ketone is a natural phenolic compound that
is the primary aroma compound of red raspberries. It is used in
perfumery, in cosmetics, and as a food additive to impart a fruity
In plants, raspberry ketone is synthesized from coumaroyl-CoA.But
since the natural abundance of raspberry ketone is very low, it is
prepared industrially by a variety of methods from chemical
intermediates.When given to mice in high doses (up to 2% of food
intake), raspberry ketone has been shown to prevent
high-fat-diet-induced elevations in body weight.This effect is
reported to stem from the alteration of lipid metabolism, increasing
norepinephrine-induced lipolysis. Although products containing this
compound are marketed for weight loss, this effect has not been
studied in humans.
Raspberry ketone, an aromatic substance in raspberries found to
reduce body fat.
Raspberry ketone is an aromatic compound found all red raspberries (Rubus
idaeus) which is extensively used in perfumery. It's chemical
structure is similar to that of zingerone, a ginger extract which
reduced obesity and is analysed elsewhere on this website. It is
also similar to that of capsaicin (the chemical that gives hot chili
peppers their "burning" quality), to synephrine (a substance found
in orange peel and known to help reduce fat and fluid retention) and
evodiamine (another fat loss ingredient). All these chemicals,
including raspberry ketone interact with fat cells and induce fat
loss via similar mechanisms.
"Anti-obese action of raspberry ketone"
In 2004 a group of Japanese researchers examined the anti-obesity
action of raspberry ketone in mice. To test the effect on obesity,
the researches in one experiment fed mice a high-fat diet including
0.5, 1, or 2% of raspberry ketone for 10 weeks. In another
experiment mice were given a high-fat diet for 6 weeks and then fed
the same high-fat diet containing 1% of raspberry ketone for the
next 5 weeks.
After 11 weeks the results were pretty amazing. Raspberry ketone did
indeed prevent the high-fat-diet-induced fat gain in the first
experiment, and decreased the fat accumulation produced by 6 weeks
of high fat diet in the second experiment. In addition, the
raspberry ketone decreased the amounts of fat accumulated in the
liver due to the high fat diet, thereby improving fatty liver. The
researchers concluded that this obesity preventing and reducing
effect was due to the potentiation of the norepinephrine-induced
lipolysis (=fat breakdown) in fat cells.
Norepinephrine is produced by the body when we exercise, therefore
the best time to consume raspberries or apply a raspberry ketone
cream on areas with excess fat, is immediately before and/or after
exercise. This is when the raspberry ketone can really perform it’s
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