Pharmaceuticals API List 3 >>
CAS number 68291-97-4
USES: This medication is used with other medications to control certain
types of seizure problems (e.g., partial seizures). This medication is
usually used when other medications have not been effective in controlling
your seizures. Controlling seizures helps to prevent injury from falling and
allows you to lead a more normal life.
Zonisamide belongs to a class of drugs known as anticonvulsants. It works by
controlling the abnormal electrical activity in the brain that occurs during
HOW TO USE: Take this medication by mouth with or without food,
usually 1-2 times daily or as directed by your doctor. Take with food or
milk if stomach upset occurs.
Your doctor will start you on a smaller dose once daily, increasing it every
2 weeks until you are taking the full dose. Swallow the capsules whole. Do
not crush or chew the capsules.
Dosage is based on your age, medical condition, blood levels of zonisamide,
and response to therapy. It may take several weeks to months until your
doctor determines the correct dose for controlling your seizures.
This medication works best when the amount of drug in your body is kept at a
constant level. Therefore, take this drug at evenly spaced intervals. To
help you remember, take it at the same time each day.
SIDE EFFECTS: Dizziness, drowsiness, trouble sleeping, tiredness,
headache, staggering walk/clumsiness, nausea, vomiting, gas, loss of
appetite, mental/mood changes (e.g., difficulty concentrating, slowed
thinking, memory loss), stomach/abdominal pain, weight loss, diarrhea,
double vision, difficulty speaking, or constipation may occur.
This medication rarely may cause mood or behavior changes, such as anxiety,
agitation, hostility, pressured/rapid speech, or thoughts of suicide. Tell
your doctor immediately if you develop unusual (possibly sudden) mood
changes. This medication may rarely cause a serious immune system problem
(systemic lupus erythematosus).
Tell your doctor immediately if you experience any of these unlikely but
serious side effects: unusual tiredness, joint/muscle aches, unusual fever,
butterfly-shaped facial rash, swollen glands, bloody/pink urine, swelling of
the feet/ankles (edema).
PRECAUTIONS: Before taking zonisamide, tell your doctor or pharmacist
if you are allergic to it; or to other sulfa-type drugs; or if you have any
Before using this medication, tell your doctor or pharmacist your medical
history, especially of: liver problems, kidney problems, severe lung
disease, anemia, low white blood cell counts, mental/mood problems
This drug may make you dizzy or drowsy; use caution engaging in activities
requiring alertness such using machinery. Avoid alcoholic beverages. Driving
is usually not allowed by law if you have new or recent seizures.
This medication can cause decreased sweating, which can lead to a serious,
possibly fatal increase in body temperature (heatstroke). Avoid becoming
overheated in hot weather, saunas, and during exercise and other strenuous
Caution is advised when using this drug in children because they may be more
sensitive to the effects of this drug, especially drowsiness, dizziness, and
MISSED DOSE: If you miss a dose, take it as soon as you remember. If
it is near the time of the next dose, skip the missed dose and resume your
usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store at room temperature at about 77 degrees F (25 degrees
C) away from light and moisture. Brief storage at 59-86 degrees F (15-30
degrees C) is permitted. Protect from heat. Discard any melted or partially
full capsules. Keep all medicines away from children